"We now have 357 separate diagnoses in DSM5; according to biological doctrine, each of these must have a distinct biological cause as a defect in the genome. None of them have ever been found but that doesn’t matter, ideology is more important than facts."
Not accurate, nor true. You should check on Large-scale GWAS, regarding genetic associations.
AND, be mindful that most common psychiatric disorders are "Polygenic".
GWAS studies, as far as I can recall, are based on as you mentioned, associations (not causal relationships) between a tiny number of genes or similar which are basically meaningless as the statistical effects are so small or there are so many different candidate genes/expressions.
They don't map onto reality either- which psychiatrist bases a diagnosis of mental disorder on an individual's polygenic score?
"We now have 357 separate diagnoses in DSM5; according to biological doctrine, each of these must have a distinct biological cause as a defect in the genome. None of them have ever been found but that doesn’t matter, ideology is more important than facts."
Not accurate, nor true. You should check on Large-scale GWAS, regarding genetic associations.
AND, be mindful that most common psychiatric disorders are "Polygenic".
GWAS studies, as far as I can recall, are based on as you mentioned, associations (not causal relationships) between a tiny number of genes or similar which are basically meaningless as the statistical effects are so small or there are so many different candidate genes/expressions.
They don't map onto reality either- which psychiatrist bases a diagnosis of mental disorder on an individual's polygenic score?